Metoprolol and metoprolol ER, also respectively known as metoprolol tartrate and metoprolol succinate, sound nearly identical and are used to treat very similar conditions. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Rubin on metoprolol tartrate to succinate conversion: It's an irrational combination. One is long acting and the other is short acting. Use one once a day or the other twice a day. Metoprolol Succinate ER is a prescription medication dispensed in a 25 mg tablet form for oral ingestion. Produced by the pharmaceutical company AstraZeneca under the brand name of Toprol XL, Metoprolol Succinate ER was approved by the FDA in 2001. Metoprolol succinate is used in the treatment of chest pain (angina),heart failure,high blood pressure. view metoprolol succinate’s uses, side-effects, drug interactions, expert advice and user faqs only on 1mg.com. Metoprolol succinate and metoprolol tartate belong to a class of drugs known as beta-blockers. These drugs treat high blood pressure and other heart conditions by blocking the effects of adrenaline on the heart. Metoprolol tartrate and metoprolol succinate are both available as generic drugs. Both medications are commonly prescribed and should be available in most pharmacies. What is the difference between metoprolol succ tab 50mg ER & metoprolol tartrate tab 50mg? - Answered by a verified Health Professional What is the difference between Metoprolol Tartrate 50 mg dosage 1/4 of tablet and Metoprolol succinate 25 mg dosage - Answered by a verified Health Professional Unless your doctor prescribed a different dose level you will be stuck with what you got, as far as the tartrate or succinate they are both of the same drug it is just in how they preform, so if you are at 25 mg succinate the same dosage level would be prescribed as 25 mg tartrate. (Detail-Document 250302: Page 3 of 3) 3. Poole-Wilson PA, Swedberg K, Cleland JG, et al. Comparison of carvedilol and metoprolol on clinical.